Microscopic Droplet Size Analysis (MDSA) of "Five Thieves' Oil" (Olejek Pieciu Zlodziei) Essential Oil after the Nebulization Process.

Nowadays, due to a higher resistance to drugs, antibiotics, and antiviral medicaments, new ways of fighting pathogens are intensively studied. The alternatives for synthesized compositions are natural products, most of which have been known in natural medicine for a long time. One of the best-known and intensively investigated groups are essential oils (EOs) and their compositions. However, it is worth noting that the method of application can play a second crucial part in the effectiveness of the antimicrobial activity. EOs possess various natural compounds which exhibit antimicrobial activity. One of the compositions which is based on the five main ingredients of eucalyptus, cinnamon, clove, rosemary, and lemon is named "five thieves' oil" (Polish name: olejek pieciu zlodziei) (5TO) and is used in natural medicine. In this study, we focused on the droplet size distribution of 5TO during the nebulization process, evaluated by the microscopic droplet size analysis (MDSA) method. Furthermore, viscosity studies, as well as UV-Vis of the 5TO suspensions in medical solvents such as physiological salt and hyaluronic acid, were presented, along with measurements of refractive index, turbidity, pH, contact angle, and surface tension. Additional studies on the biological activity of 5TO solutions were made on the P. aeruginosa strain NFT3. This study opens a way for the possible use of 5TO solutions or emulsion systems for active antimicrobial applications, i.e., for surface spraying.

Spray curtains as devices for surface spraying during the SARS-CoV-2 pandemic.

Counteracting the spread of the SARS-CoV-2 virus is a current and important problem. A crucial issue in this area is the disinfection of various surfaces, as well as the air itself. For this purpose, devices such as foggers, which have different designs, are used. The appropriate size of droplets and their distribution determines the effectiveness of disinfectants. The paper presents droplet size distributions and characteristic mean droplet diameters, which are obtained with the use of a conical pressure-swirl atomizer. For the purpose of the analysis, the laser diffraction method was used. The influence of gas pressure and the distance from the atomizer's orifice on the spray angle and the distance between the nozzles on the spray curtain was also demonstrated.

Influence of Spray Nozzle Operating Parameters on the Fogging Process Implemented to Prevent the Spread of SARS-CoV-2 Virus

This article reports the results of a study into the effect of operating parameters on the occurrence and course of gas–liquid two-phase phenomena during the fogging process carried out with the use of a conical pressure-swirl nozzle. Four alternatives of the stub regulation angles and four values of pressure of air supply to the nozzle were tested as part of the current research. The range of the investigated variables was common for the operation of fumigators used to prevent the spread of SARS-CoV-2 virus. The liquid flow rate (weighting method), the field of velocity, and turbulent flow intensity factor, as well as velocity profiles over the section of 1 m from the nozzle were determined using the particle image velocimetry (PIV) technique. The obtained results were correlated with the measurements of the diameters of spray droplets using the laser light scattering (LLS) technique. On the basis of this research, a dependence between the nozzle parameters and the spray cone pattern was identified in terms of dynamics and droplet diameter distribution. As a result of the research, a wide range of parameters were identified in which the fogging process was carried out in a stable and repeatable manner. There were exceptions to this rule only in the cases when there was a deficiency of the liquid necessary to generate a two-phase mixture.

Analysis of the Possibility of Disinfecting Surfaces Using Portable Foggers in the Era of the SARS-CoV-2 Epidemic

The SARS-CoV-2 pandemic has resulted in the need for increased surface disinfection. For this purpose, biocides, UV-C radiation, or ozonation can be used. The most commonly used are biocides that can be deposited on the surface with the use of various devices, including foggers. The disinfection efficiency is related to the size of the aerosol droplets formed and their distribution. This paper specifies the distribution of droplet diameters and mean droplet diameters obtained during the use of a commercial fogger. It was shown that the droplet diameters formed were mainly in the range of up to 30–40 μm. A ceramic filter allowed for a larger number of smaller droplets and a limitation in the number of droplets with larger diameters. The results are important in the context of fighting the virus in hard-to-reach places where battery devices can be used.